Vibration after 80mph

[Luisf701]

2015 mustang vibration after 80mph replaced wheels and tires. Got an alignment got didn't fix it. Replaced bushing carrier support for driveshaft still getting the same vibration. Fbo car never had this issue 100k miles

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[Cobra Jet]

Check the u-joints.

Check to make sure none of the driveshaft bolts have backed out at the front and rear flange - as well as those at the center carrier.

Also check run out of the rear pinion flange and the trans flange.

It’s also possible you could have a rear diff that could have an issue too.