Gregs24
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It is very complex. It is thought a single dose of vaccine after a wild infection will provide better immunity than infection alone. But you have to consider the different delivery methods, local and humoral immunity, differing types of immunity and defence mechanisms within individual subjects. That is before you consider what benefits you are trying to achieve, such as prevention of illness, prevention of infection, prevention of onwards spread, in varying degrees.Do you think infection after vaccination will offer the same level of immunity as infection unvaccinated(setting aside the benefits of vaccination)?
I do have some worries about ADE(probably unfounded) but if question 1 is yes, could this offset any problem we could encounter with ADE?
More detail in the previous post
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